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“Three Pronged Approach”
Early in 2007 Allergy Therapeutics PLC (ATp) launched a project to upgrade one
of their manufacturing processes for the treatment of allergies. ATp have a
sterile range of tyrosine based products which are used to desensitise patients
who are allergic to known allergens especially Pollens.
ATp enlisted BPE to validate, design and project manage the
£1.7M venture. Following a successful tender, Suncombe were awarded the contract
for the detailed design and build of the 8 preassembled units that comprised the
process. The equipment design
incorporates semi automated operation by a bespoke control system, Clean in
Place, Steam in Place together with the latest technology for the transfer of
solutions between vessels.
Suncombe designed, developed, drew and specified Process vessels, Skids,
Pipework and an Automation System comprising of Siemens PLCs, Siemens HMIs and
paperless Chart Recorders, providing a 21CFR11 compliant batch control
environment.
The plant has now been delivered to site and is currently undergoing an
intensive qualification programme. It is anticipated that the first
qualification batches will be manufactured in the second quarter of 2008. The
above photograph shows one of the main skids used in the manufacturing process.
The project has been
demanding and rewarding, the teams working closely together to overcome
challenges throughout the life cycle of the project.
It is hoped that this joint venture will be one of the first to be
undertaken by the ATp, BPE and Suncombe.
Rick Poland
UK
Manufacturing &
Engineering Manager
10thDecember 2007
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